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Featured Publications

New Paper Published

Research carried out by Professor Colin Campbell's group, with collaborators in the University of Edinburgh's School of Biology, Jerusalem and Liege has recently been published online in the Proceedings of theNational Academy of Sciences of the United States of America. The paper is titled "Intracellular redox potential is correlated with miRNA expression in MCF7 cells under hypoxic conditions ".

New Paper Finds Crystal Polymorphs of Trial Cancer Drug

Prof Colin Pulham and Dr Sumit Konar from the School of Chemistry recently collaborated with University College London and Eli Lilly and Company on a paper that has now been accepted in JACS. The paper details research that comnbined multiple methods to find the crystal structures of all 10 unsolvated polymorphs of galunisertib, which is currently undergoing trials as a cancer drug.

Structure and Motion Captured by Ultrafast X-rays

Dr Adam Kirrander and his team have published a paper in Nature Chemistry with collaborators at Brown University and the SLAC National Accelerator Laboratory. The experiment exploits the brightness and high time resolution of the new x-ray free-electron laser, LCLS in California, to capture the vibrational motion of an excited molecule in detail.

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New Paper in Journal of Lipid Research

The Campopiano group have published a paper in the May issue of JLR where they describe the kinetics differences between the human and bacterial forms of serine palmitoyltransferase (SPT) - the first enzyme in sphingolipid biosynthesis.

The paper is also the first publication between the University of Edinburgh and The Rosalind Franklin Institute (RFI) in collaboration with RFI Director Prof. Jim Naismith.