Dr Uwe Schneider

Lecturer in Organic Chemistry / Asymmetric Catalysis

Contact details

Address

Street

Room 227
University of Edinburgh
Joseph Black Building
David Brewster Road
Edinburgh
EH9 3FJ

City
Post code

Research summary

‘Green/Sustainable’ Chemistry; (Asymmetric) Catalysis; C-H & C-C Bond Activation; Low-Oxidation State Main Group Chemistry; Base, Acid, Dual, Ambiphilic, & FLP Catalysis; Transition Metal-Like Redox Catalysis; Bond Activation in Small Molecules.

Research Overview

Current projects deal with the development of base, acid, dual, ambiphilic, and FLP catalysis as well as transition metal-like redox catalysis by exploiting the unique characteristics of non-metal [C(0), carbones -- Si(0), silylones -- N(I), nitreones -- P(I), phosphinidenes] and main group metal species in their respective low-oxidation states [Al/Ga/In(I), group XIII -- Ge/Sn(II), group XIV -- Sb/Bi(III), group XV].  These under-explored catalysts are exploited in transition metal-free C-H/C-C/C-X bond cleavage and small molecule activation.

  • Y. Zhou, Z.-N. Zhao, Y.-L. Zhang, J. Liu, Q. Yuan, U. Schneider and Y.-Y. Huang Brønsted Acid-Catalyzed General Petasis Allylation and Isoprenylation of Unactivated Ketones Chem. Eur. J. 2020, 26, doi.org/10.1002/chem.202001594 (full paper)
  • Z.-H. Cao, Y.-H. Wang, S. J. Kalita, U. Schneider and Y.-Y. Huang Phosphine-Catalyzed [4+1] Cycloadditions of Allenes with Methyl Ketimines, Enamines, and a Primary Amine Angew. Chem. Int. Ed. 2020, 59, 1884 (research article)
  • F. Cheng, S. J. Kalita, Z.-N. Zhao, X. Yang, Y. Zhao, U. Schneider, N. Shibata and Y.-Y. Huang Diastereodivergent Asymmetric 1,3-Dipolar Cycloaddition of Azomethine Ylides and b-Fuoro-Alkyl Sulfones Angew. Chem. Int. Ed. 2019, 58, 16637 (research article)
  • J. Dai, W. Dan, U. Schneider and J.-R. Wangb-Carboline Alkaloid Monomers and Dimers: Occurrence, Structural Diversity, and Biological Activities Eur. J. Med. Chem. 2018, 157, 622 (review)
  • W. Bao, H. Kossen and U. Schneider Formal Allylic C(sp3)-H Bond Activation of Alkenes Triggered by a Sodium Amide J. Am. Chem. Soc.2017, 139, 4362 (communication)
  • B. Qin and U. Schneider Catalytic Use of Elemental Gallium for Carbon-Carbon Bond Formation J. Am. Chem. Soc. 2016, 138, 13119 (communication)
  • Y.-Y. Huang, C. Cai, X. Yang, Z.-C. Lv and U. Schneider Catalytic Asymmetric Reactions with N,O-Aminals ASC Catal. 2016, 6, 5747 (review)
  • J. Dai, N. Li, J.-R. Wang and U. Schneider Fruitful Decades for Canthin-6-ones 1952–2015: Biosynthesis, Chemistry, and Biological Activities Molecules 2016, 21, 493 (review)
  • V. Ananikov, X. Liu and U. Schneider Catalysis to Build Molecular Complexity with Atomic Precision Chem. Asian. J. 2016, 11, 328 (invited editorial)
  • S. Kobayashi, T. Endo, T. Yoshino, U. Schneider and M. Ueno Allylation Reactions of Aldehydes with Allyl Boronates in Aqueous Media: Unique Reactivity and Selectivity Chem. Asian. J. 2013, 8, 2033 (full paper)
  • U. Schneider Catalytic Asymmetric Conjugate Reactions (Wiley-VCH 2010; ed. A. Cordova) Appl. Organometal. Chem. 2012, 26, 321 (invited book review)
  • U. Schneider, Y.-Y. Huang, A. Chakrabarti, H. T. Dao, N. Morita and S. Kobayashi Boron-Based Pronucleophiles in Catalytic (Asymmetric) C(sp3)-Allyl Cross-Couplings Pure Appl. Chem. 2012, 84, 2417 (invited account)
  • U. Schneider and S. Kobayashi Low-Oxidation State Indium-Catalyzed C-C Bond Formation Acc. Chem. Res. 2012, 45, 1331 (invited account)
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