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Professor Alison Hulme quoted on BBC

Professor Alison Hulme at University of Edinburgh, explains that the same process applies in click chemistry. "Two chemical partners are perfectly designed to match each other so that when they come into contact with each other in the right environment, they just click together," she told BBC News. But at first it could not be used in living cells - essential for understanding disease - because it involved the use of copper which kills cells. Professor Bertozzi's ground-breaking discovery made click chemistry work in living cells.

Teaching an Old Dog New Tricks?

The aldol reaction is amongst the oldest and most established reactions in organic chemistry. However, despite being an intensive area of research, access to aldol products, β-hydroxy ketones, has been limited to the use of aldehydes and ketones. Using born catalysis the Thomas group have overcome this and allowed esters and lactones to be used to access aldol products.

Chemical ‘Egg-boxes’ Could Crack Rare-earth Element Separations

Rare-earth element dependent technologies are crucial for renewable energy generation and storage, electric vehicles, and electronic displays. However, access to these metals, in large part due to difficulties in their separation, is limited and is dominated by China. Improving how rare-earth elements are separated is essential to prevent metal supply derailing climate efforts.

Study Seeks to Address Concerns of Pregnant and Breastfeeding Lab Scientists

The study will allow researchers to better understand the barriers to combining pregnancy and breastfeeding in academic careers within physical sciences.

Examples of best practice and missed opportunities will be identified in order to better accommodate pregnant or breastfeeding staff and students in laboratory work and teaching.

Funding for the project is being provided by the EPSRC’s Vacation Internships scheme.

Angewandte Chemie Hot Paper

Hydrogen bonds are everywhere. They determine the structure and properties of water and materials. In life, hydrogen bonds govern the structure of proteins, DNA, RNA, and their associated molecular recognition processes. Clearly, biology has mastered the use of hydrogen bonds, yet such interactions occur in the presence of one of the most competitive hydrogen bonding solvents known; water. However, water is such a good hydrogen bond donor and acceptor that the energy of a single hydrogen bond is effectively nullified by the competing interactions with the solvent.