Mass Spectrometry

The Mass Spectrometry Facility at the School of Chemistry is home to The Scottish Instrumentation and Resource Centre for Advanced Mass Spectrometry (SIRCAMS), one of the most advanced mass measurement facilities in Europe.

Why choose the University of Edinburgh School of Chemistry as a partner for your Mass Spectrometry needs?

  • The facility houses a wide range of mass spectrometry platforms and the world class team have expertise in the mass analysis of a diverse range of analytes – from small molecules to complex biomolecular systems.

  • The facility also has a long history of collaborating with academic and industrial groups worldwide, offering excellence in mass spectrometry analysis, training and consultancy.

MS Lab

Equipment Available

  • A range of LC-MS and GC-MS platforms 

  • Two FT-ICR MS instruments

  • Ion-mobility equipped Q-Tof instruments (Waters)

  • MALDI-ToF/ToF (Bruker Daltonics)

  • Orbitrap Ascend Structural Biology Tribrid MS (Thermo Fisher Scientific) - installation early 2026. Funded by BBSRC on behalf of UK Research and Innovation

BBSRC logo

SERVICES AVAILABLE

  • Small Molecule Characterisation using accurate mass determination and tandem mass spectrometry. LC-MS and GC-MS capabilities

  • Complex Mixture Analysis. Ultra-high-resolution mass analysis for the chemical profiling of complex chemical mixtures such as petrochemicals and fuels, environmental samples, and for food and beverage analysis

  • Biomolecular Mass Spectrometry including:

    • protein intact mass determination

    • protein PTM characterisation

    • automated protein-ligand screening

    • structural mass spectrometry analysis

  • Mass Spectrometry Imaging. Untargeted spatial imaging of metabolites from biological tissue sections using MALDI imaging techniques at high mass resolution

     

    Industrial Themes: Pharma and healthcare, Industrial biotechnology, Food and drink, Chemical process R&D.

  • For more information please contact Dr Van Kelly

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